Senior Trooper Joseph Birt said two vehicles were involved in the accident that occurred just inside the city limits of Lindale.
Trooper Richard Hoover said an 81-year-old Lindale man was driving east in the inside westbound lane of the highway in a Toyota truck, before colliding head-on with a Ford F-250 truck.
The 81-year-old man died at the scene. As of 10 p.m., officers were working to notify next of kin.
DPS and Lindale Fire were on the scene. The wreck blocked westbound lanes of Interstate 20 Tuesday night, and traffic was diverted onto the shoulder.