A state trooper at the scene said two vehicles were involved in the accident that occurred just inside the city limits of Lindale.
The trooper said that in one vehicle were four people - two men, one woman and an 11-month-old who were taken to East Texas Medical Center in Tyler with minor injuries. The other vehicle was occupied by a man who died in the wreck, the trooper said.
No other details about the accident were available as of 10 p.m.
DPS and Lindale Fire were on the scene. The wreck blocked westbound lanes of Interstate 20 Tuesday night, and traffic was diverted onto the shoulder.