Smith County Fire Marshal Jim Seaton said a neighbor heard loud pops, looked out a window and saw the home on fire.
Seaton said Gladewater firefighters arrived about 3:30 a.m. Monday and found flames engulfing the home.
A search began after authorities determined a car on the property belonged to the victim and her husband.
“The husband was found in Good Shepherd Hospital, where he has been undergoing treatment for an unrelated matter. We did however, find her body in the debris,” he said.
Seaton said the woman, Sandra Rowell, was found adjacent to a chair in the back bedroom.
Fire departments from Jackson and Winona also responded.
Seaton said Mrs. Rowell's body was sent for an autopsy. The fire's cause remained under investigation.